S
| Town name | Postal code |
| Sabie | 1260 |
| Sabie | 1290 |
| Sakhile | 2431 |
| Saldanha | 7282 |
| Saldanha | 7382 |
| Saldanha | 7395 |
| Saltville | 6059 |
| Sandton | 2172 |
| Sandton | 2196 |
| Sannieshof | 2760 |
| Sasolburg | 1946 |
| Sasolburg | 1947 |
| Sasolburg | 1948 |
| Sasolburg | 1949 |
| Sasolburg | 9580 |
| Saulspoort | 0318 |
| Saulspoort | 0374 |
| Saulspoort | 0399 |
| Schweizer-Reneke | 2775 |
| Schweizer-Reneke | 2780 |
| Schweizer-Reneke | 2786 |
| Scottburgh | 4180 |
| Scottburgh | 4181 |
| Scottburgh | 4182 |
| Scottburgh | 4183 |
| Scottburgh | 4184 |
| Scottburgh | 4185 |
| Scottburgh | 4186 |
| Scottsville | 3204 |
| Scottsville | 3252 |
| Scottsville | 3760 |
| Scottsville | 3770 |
| Sebokeng | 1914 |
| Sebokeng | 1907 |
| Sebokeng | 1980 |
| Sebokeng | 1981 |
| Sebokeng | 1983 |
| Sebokeng | 1984 |
| Secunda | 2300 |
| Secunda | 2301 |
| Secunda | 2302 |
| Sedgefield | 6573 |
| Sekhukhune | 1058 |
| Sekhukhune | 1063 |
| Sekhukhune | 1064 |
| Sekhukhune | 1127 |
| Selosesha | 9783 |
| Senekal | 9600 |
| Senekal | 9485 |
| Seshego | 0795 |
| Seshego | 0699 |
| Seshego | 0784 |
| Seshego | 0751 |
| Settlers | 0430 |
| Sezela | 4215 |
| Shakaskraal | 4430 |
| Shallcross | 4093 |
| Sharpeville | 1913 |
| Sharpeville | 1928 |
| Shelly Beach | 4240 |
| Shelly Beach | 4265 |
| Shiluvane | 0873 |
| Shongwe Mission | 1331 |
| Shongwe Mission | 1332 |
| Shongwe Mission | 1335 |
| Shongwe Mission | 1336 |
| Shongwe Mission | 1337 |
| Sibasa | 0906 |
| Sibasa | 0907 |
| Sibasa | 0926 |
| Sibasa | 0955 |
| Sibasa | 0968 |
| Sibasa | 0969 |
| Sibasa | 0970 |
| Sibasa | 0971 |
| Sibasa | 0972 |
| Sibasa | 0973 |
| Sibasa | 0974 |
| Sibasa | 0975 |
| Sibasa | 0976 |
| Sibasa | 0977 |
| Sibasa | 0979 |
| Sibasa | 0980 |
| Sibasa | 0988 |
| Sibasa | 0989 |
| Sibasa | 0990 |
| Sibasa | 0993 |
| Sibasa | 0994 |
| Sibasa | 0995 |
| Sibasa | 0996 |
| Silverton | 0170 |
| Silverton | 0184 |
| Simon’S Town | 7975 |
| Simon’S Town | 7995 |
| Simonstad | 7975 |
| Siyabuswa | 0462 |
| Siyabuswa | 0469 |
| Siyabuswa | 0472 |
| Siyabuswa | 0475 |
| Siyabuswa | 0477 |
| Siyabuswa | 0493 |
| Siyabuswa | 0494 |
| Siyabuswa | 0495 |
| Siyabuswa | 1030 |
| Skilpadfontein | 0431 |
| Skukuza | 1351 |
| Skukuza | 1353 |
| Skukuza | 1354 |
| Skukuza | 1356 |
| Smithfield | 9966 |
| Soekmekaar | 0810 |
| Somerset East | 5850 |
| Somerset West | 7110 |
| Somerset West | 7130 |
| Somerset West | 7131 |
| Somerset West | 7133 |
| Somerset West | 7134 |
| Somerset West | 7135 |
| Somerset-Wes | 7130 |
| Soshanguve | 0152 |
| Soshanguve | 0164 |
| Southfield | 7800 |
| Southseas | 6172 |
| Sovenga | 0763 |
| Sovenga | 0727 |
| Soweto | 1803 |
| Soweto | 1804 |
| Soweto | 1808 |
| Soweto | 1809 |
| Springbok | 8893 |
| Springbok | 8240 |
| Springbok | 8241 |
| Springbok | 8242 |
| Springbok | 8247 |
| Springbok | 8251 |
| Springbok | 8282 |
| Springfontein | 9917 |
| Springs | 1558 |
| Springs | 1559 |
| Springs | 1562 |
| Springs | 1563 |
| Springs | 1564 |
| Springs | 1565 |
| Springs | 1566 |
| Springs | 1567 |
| Springs | 1568 |
| Springs | 1569 |
| Springs | 1570 |
| Springs | 1571 |
| Springs | 1572 |
| Springs | 1574 |
| Springs | 1575 |
| Springs | 1577 |
| Springs | 1578 |
| St Lucia Estuary | 3936 |
| St Wendolins | 3609 |
| Standerton | 2425 |
| Standerton | 2429 |
| Standerton | 2430 |
| Standerton | 2431 |
| Standerton | 2432 |
| Standerton | 2433 |
| Standerton | 2434 |
| Standerton | 2435 |
| Standerton | 2436 |
| Stanger | 3815 |
| Stanger | 4449 |
| Stanger | 4450 |
| Stanger | 4451 |
| Stanger | 4452 |
| Stanger | 4453 |
| Stanger | 4454 |
| Stanger | 4455 |
| Stanger | 4456 |
| Stanger | 4457 |
| Stanger | 4470 |
| Stanger | 4490 |
| Steadville | 3373 |
| Steenberg | 7945 |
| Stellenbosch | 7600 |
| Stellenbosch | 7601 |
| Stellenbosch | 7602 |
| Stellenbosch | 7603 |
| Stellenbosch | 7604 |
| Stellenbosch | 7605 |
| Stellenbosch | 7607 |
| Stellenbosch | 7608 |
| Stellenbosch | 7611 |
| Stellenbosch | 7612 |
| Stellenbosch | 7613 |
| Stellenbosch | 7614 |
| Stellenbosch | 7615 |
| Sterkspruit | 9762 |
| Sterkstroom | 5425 |
| Steynsburg | 5920 |
| Steytlerville | 6250 |
| Stilbaai | 6674 |
| Stilfontein | 2551 |
| Stilfontein | 2552 |
| Stilfontein | 2553 |
| Stilfontein | 2554 |
| Stilfontein | 2556 |
| Stilfontein | 2560 |
| Stilfontein | 2562 |
| Still Bay | 6674 |
| Still Bay | 6675 |
| Still Bay | 6676 |
| Strand | 7140 |
| Strand | 7144 |
| Strand | 7151 |
| Strandfontein | 7798 |
| Strathavon | 2196 |
| Strathavon | 2031 |
| Strubens Valley | 1724 |
| Strubens Valley | 1735 |
| Strubensvallei | 1735 |
| Strubensvallei | 1724 |
| Strydenburg | 8765 |
| Stutterheim | 4930 |
| Stutterheim | 4934 |
| Stutterheim | 4935 |
| Sundra | 2200 |
| Sundra | 2211 |
| Superbia | 0788 |
| Superbia | 0778 |
| Superbia | 0779 |
| Sutherland | 6920 |
| Swartbooistad | 0418 |
| Swartklip | 0375 |
| Swartklip | 0351 |
| Swartkops | 6210 |
| Swartruggens | 2835 |
| Swellendam | 6740 |
| Swellendam | 6742 |
| Swellendam | 6743 |
